It is also described as complementary (not redundant) with tesamorelin or sermorelin, since both of those are GHRH analogs that pair with ipamorelin's GHRP action rather than duplicating it
Singh, R., Al Khalili, Y
Safety and Tolerability As with many metabolic therapies, the most commonly reported side effects in the Retatrutide trial included gastrointestinal symptoms such as nausea, diarrhea, constipation, vomiting, and decreased appetite, patterns seen with many gut-hormone modulators
In addition, GLP-1 therapies may modify bile acid metabolism, which is known to shape microbial diversity and metabolic signaling pathways
GHK has also been found to decrease the release of iron from ferritin
Wegovy has also been studied in adolescents with obesity in specific settings